Caliper Life Sciences IVIS Lumina II Imaging System

The IVIS Lumina II is capable of imaging fluorescent,
bioluminescent and phosphorescent reporters present
in living small animals (mice, rats, fish etc.).
It can be used to study in living animals
(1) the expression of genes using bioluminescent
or fluorescent reporters,
(2) the biodistribution of fluorescent labeled compounds,
(3) tumor growth and metastasis,
(4) viral or bacterial infections,
(5) the migration of (stem) cells, etc.
The system includes a sensitive deep-cooled CCD camera,
a light-tight imaging chamber, gas anesthesia,
a temperature controlled stage,
and image analysis using spectral un-mixing software.
Eighteen band-pass emission filters covering
a spectrum between 500nm and 850nm
are available in the laboratory.
These high resolution filters allow the simultaneous detection
of multiple fluorescent probes in one animal.
Up to 5 mice or two rats
can be imaged simultaneously with the IVIS Lumina II.