Spectromax M2 Microplate Reader

Multi-detection capability: Supports absorbance,
fluorescence (top-read), and with the M2e,
adds bottom-read fluorescence, luminescence,
and time-resolved fluorescence (TRF).
Top- and bottom-read fluorescence:
Bottom-read only on the M2e for enhanced cell
based assay sensitivity.
Dual-mode cuvette port:
Enables standard spectrophotometry outside of microplate format.
Dual monochromators: Selectable excitation and emission wavelengths (1 nm increments) without the need for filters.
PathCheck® Technology: Automatically normalizes optical pathlengths for absorbance, ensuring accurate, cuvette-equivalent readings.
Well volume sensor: Prevents errors from low-volume or uneven well filling.
Instrument and software validation: Compatible with SoftMax® Pro software for data analysis and 21 CFR Part 11 compliance, supporting regulated lab environments.
Robot compatible: Integration-ready with automation systems and plate stackers for high-throughput workflows.

Typical Applications
ELISA
DNA/RNA/Protein quantification
Enzyme kinetics
Cell viability and cytotoxicity (M2e preferred)
FRET and TR-FRET
Luminescence assays (M2e)
Low-volume or cuvette-based protocols