Tecninox Fermenter/Bioreactor

Fermenter geometry 3:1
Fermenter head without sharp edges to improve cleaning, GMP gasket
Fermenter head with TC connections of various sizes (3/4, ½, 1), use them for additions, feeding, inoculation, etc.
Working volume for 36L bioreactor: 20L, Minimum working volume 7.5L (positioning holder for probes)
Working volume for 74L bioreactor: 50L, dependent on position of last impeller
Operational pressure range: -0.01 to 3. 00 bar g
Double mechanical seal
Motor position: overhead motor shaft, as close as possible to sparger and bottom
Impellers 3 Rushton / 3 Pitched Blade
Configurable motor speed 50-1500 rpm
Toroidal sparger with possibility of coupling and uncoupling
Exhaust gas condenser
Integrated CIP system
Exhaust gas management: double exhaust gas line after the outlet filter (the gas line must divide into two branches: one direct to the spent gas analysis system (airnova) and the other to the drain/waste)
Aeration 0 to 2. 5 VVM
Inlet air from above and from the sparger, with flowmeter
O2 inlet: 0 to 2.5 VVM, O2 inlet from above and from the sparger, with flowmeter
N2 inlet: 0 to 1 VVM, N2 inlet from above and from the sparger, with flowmeter
CO2 inlet 0 to 1 VVM, CO2 inlet from above and from the sparger, with flowmeter
Head pressure adjustment: automatic
Fixed speed pump with remote control
Variable speed pumps, two bottom valves
Bottom valve filter
Integrity test: integrated housing to perform in situ integrity test
Loading soil hole for manual loading
Fixed speed Peristaltic pumping, position adjacent to bioreactor pH, for control of acid/ base, CO2
Feeding base inlet via Sacova valve with ingold control
Utilities needed to run:
Electrical requirements: 380v, 50Hz
Steam feed: 3 - 9 bar
Clean steam: 3 bar g
Purified water
Compressed air 8 bar g
Nitrogen: 8 bar
Refrigerated water: 9 - 12 deg C
Oxygen: 12 bar
CO2: 8 bar
Softened water
Drainage and discharge